The mechanism and interrelationships of the flocculation tests.

So many flocculation tests have been developed during the last few years that the time appears ripe to attempt a critical review of the mechanism and usefulness of some of the more popular procedures. Although many of these tests were developed primarily in relation to liver disease, where they are of proved value, it is generally recognized that they are not all specific in this respect. There is no doubt, however, that they can throw useful light on the qualitative and quantitative changes in the pattern of the circulating proteins in disease. Earlier work in this field was recently reviewed by one of us (Maclagan, 1948) and the present paper deals with more recent contributions.